Publications by authors named "Aaron B Boothby"
Article Synopsis
- Up to one-third of patients with blood cancers who have received multiple transfusions develop immune-mediated issues that make platelet transfusions less effective, known as platelet transfusion refractoriness.
- This study analyzed 2012 platelet transfusions in 73 patients to examine how HLA antibodies and other patient factors influence the effectiveness of these transfusions, specifically looking at their impact on the corrected count increment (CCI) after 2 and 24 hours.
- Results showed that high levels of donor-specific antibodies, certain blood type mismatches, and other specific conditions negatively affected immediate posttransfusion platelet counts, suggesting that using a computerized algorithm for donor-recipient matching could improve outcomes in these patients.
