Efficacy of vaginally applied estrogen, testosterone, or polyacrylic acid on vaginal atrophy: a randomized controlled trial.

Objective: Vaginal atrophy is a common chronic condition among postmenopausal women that can affect their quality of life. Recent studies have evaluated new treatment alternatives for vaginal atrophy; however, few therapeutic options have been thoroughly evaluated. This study aimed to compare the effectiveness and adverse effects of estrogen, testosterone, polyacrylic acid, and placebo lubricant for the treatment of postmenopausal women with vaginal atrophy.

Subjective urinary urgency in middle age women: A population-based study.

Aims: There are few population-based studies evaluating the epidemiology of overactive bladder syndrome (OAB) in women, especially in the climacteric stage where there is a decrease in estrogen production. This study aimed to assess the prevalence of OAB and associated factors in climacteric Brazilian women.

Methods: A descriptive, exploratory, cross-sectional study was conducted between September 2012 and June 2013 with 749 women (a population-based household survey).

Sexual function and quality of life in women with cervical cancer before radiotherapy: a pilot study.

Purpose: To achieve a better understanding of issues related to sexual function and quality of life (QOL) of women with cervical cancer before radiotherapy treatment.

Methods: A pilot study with 80 women with cervical cancer from Jan/2013 to Mar/2014. The outcome variables were sexual function assessed using the Female Sexual Function Index (FSFI) and QOL, assessed using the World Health Organization questionnaire.

[Factors associated with menopausal symptoms in women from a metropolitan region in Southeastern Brazil: a population-based household survey].

Purpose: To determine the average age at the onset of menopause and to investigate menopausal symptoms in women in a metropolitan region in Southeastern Brazil.

Methods: A descriptive, exploratory, cross-sectional study was conducted with 749 women (a population-based household survey). The dependent variable was the intensity of menopausal symptoms assessed by th Menopause Rating Scale (MRS).

The epidemiology and management of postmenopausal osteoporosis: a viewpoint from Brazil.

Brazil has an aging population, with an associated increase in the prevalence of chronic diseases. Postmenopausal osteoporosis is of particular concern because it leads to an increased risk of fractures, with subsequent negative impacts on health in older women. In recent years, efforts have been made to better understand the epidemiology of osteoporosis in Brazil, and to manage both direct and indirect costs to the Brazilian health care system.

Cancer in Women over 50 Years of Age: A Focus on Smoking.

The increase in life expectancy worldwide has resulted in a greater prevalence of chronic non-communicable diseases. This study aims to evaluate the prevalence and factors associated with the occurrence of cancer among Brazilian women over the age of 50. A cross-sectional study with 622 women over the age of 50 was performed using a population survey.

Omentum for Mammary Disorders: A 30-Year Systematic Review.

Purpose: Although the safety of applying omentum to the female breast for total breast reconstruction is controversial, it has recently been used to treat certain mammary disorders as well. A systematic review was therefore conducted to analyze and establish the suitability and safety of applying omentum to the breast.

Methods: Covereing the interval from January 1984 to December 2013, we performed searches in MEDLINE, Embase, SciELO, and Google-Scholar for original articles describing the applicability of greater omentum to the breast and its clinical complications.

Disability and multimorbidity in women older than 50 years: a population-based household survey.

Objective: This study aims to evaluate the prevalence of disability and associated factors in Brazilian women older than 50 years.

Methods: We conducted a cross-sectional study (in the form of a population survey) of 622 women older than 50 years and residing in Campinas, Brazil. Disability was assessed through a questionnaire with seven items and defined as "being completely unable to perform any of them.

Factors associated with the onset of hypertension in women of 50 years of age or more in a city in Southeastern Brazil.

Purpose: To evaluate factors associated with hypertension in Brazilian women of 50 years of age or more.

Methods: A cross-sectional population based study using self-reports. A total of 622 women were included.

The effect of soy dietary supplement and low dose of hormone therapy on main cardiovascular health biomarkers: a randomized controlled trial.

Purpose: To assess the effects of a soy dietary supplement on the main biomarkers of cardiovascular health in postmenopausal women compared with the effects of low-dose hormone therapy (HT) and placebo.

Methods: Double-blind, randomized and controlled intention-to-treat trial. Sixty healthy postmenopausal women, aged 40-60 years, 4.

[Association between breast arterial calcifications and cardiovascular risk factors in menopausal women].

Purpose: To analyze associations between mammographic arterial mammary calcifications in menopausal women and risk factors for cardiovascular disease.

Methods: This was a cross-sectional retrospective study, in which we analyzed the mammograms and medical records of 197 patients treated between 2004 and 2005. Study variables were: breast arterial calcifications, stroke, acute coronary syndrome, age, obesity, diabetes mellitus, smoking, and hypertension.

Immunohistochemical expression of estrogen and progesterone receptors in endometrial polyps: A comparison between benign and malignant polyps in postmenopausal patients.

The aim of the present study was to evaluate estrogen receptor (ER) and progesterone receptor (PR) expression in the glandular epithelium and stroma of benign and malignant endometrial polyps of postmenopausal patients. A total of 1,050 females underwent surgical hysteroscopy at the Professor Dr José Aristodemo Pinotti Women's Hospital, Center for Integral Attention to Women's Health of the State University of Campinas, between January 1998 and December 2008. Of the total number, 390 postmenopausal females with endometrial polyps were included in the study.

[Climacteric syndrome in a Northeastern Brazilian city: a household survey].

Purpose: To assess the prevalence of Climacteric Syndrome (CS) in women from a municipality of Northeastern Brazil which is less developed socioeconomically.

Methods: A prospective household survey was performed in São Luís, Maranhão, Brazil with 1,210 climacteric women aged 45 to 60 years. Interviews were applied using previously tested standard questionnaires from April to July 2008.

Expression of hormone receptors, Bcl‑2, Cox‑2 and Ki67 in benign endometrial polyps and their association with obesity.

The present study examined the immunoexpression of the estrogen receptor (ER), the progesterone receptor (PR), B‑cell lymphoma 2 (Bcl‑2), cyclooxygenase‑2 (Cox‑2) and Ki67 in endometrial polyps and their association with obesity. In total, 515 premenopausal and postmenopausal females undergoing hysteroscopy with histological diagnosis of benign polyps were included. The immunohistochemical expression of the ER, PR, Bcl‑2, Cox‑2 and Ki67 was compared between obese and non‑obese females.

Cardiovascular risk in middle-aged breast cancer survivors: a comparison between two risk models.

Purpose: It was to assess the risk of cardiovascular disease (CVD) in breast cancer survivors (BCS).

Methods: This cross-sectional study analyzed 67 BCS, aged 45 -65 years, who underwent complete oncological treatment, but had not received hormone therapy, tamoxifen or aromatase inhibitors during the previous 6 months. Lipid profile and CVD risk were evaluated, the latter using the Framingham and Systematic COronary Risk Evaluation (SCORE) models.

Efficacy of vaginally applied estrogen, testosterone, or polyacrylic acid on sexual function in postmenopausal women: a randomized controlled trial.

Introduction: Female libido is multifactorial and complex. Declining estrogen levels in postmenopausal women affects vaginal function.

Aim: The aim of this study was to evaluate female sexual function after using topical estrogen, testosterone, or polyacrylic acid as vaginal lubricants with K-Y jelly as a placebo lubricant.

Factors associated with fragility fractures in women over 50 years of age: a population-based household survey.

Purpose: To analyze the prevalence of and factors associated with fragility fractures in Brazilian women aged 50 years and older.

Methods: This cross-sectional population survey, conducted between May 10 and October 31, 2011, included 622 women aged >50 years living in a city in southeastern Brazil. A questionnaire was administered to each woman by a trained interviewer.

Self-perception of sexual life and associated factors: a population study conducted in women aged 50 or more years.

Purpose: To evaluate the prevalence of women aged 50 years or more who are sexually active and their self-perception with respect to their sexual lives. Associated factors were also assessed.

Methods: A cross-sectional, population-based, self-reported household survey involving 622 Brazilian women aged 50 years or more.

Accuracy of sonography and hysteroscopy in the diagnosis of premalignant and malignant polyps in postmenopausal women.

Purpose: To evaluate the accuracy of sonographic endometrial thickness and hysteroscopic characteristics in predicting malignancy in postmenopausal women undergoing surgical resection of endometrial polyps.

Methods: Five hundred twenty-one (521) postmenopausal women undergoing hysteroscopic resection of endometrial polyps between January 1998 and December 2008 were studied. For each value of sonographic endometrial thickness and polyp size on hysteroscopy, the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated in relation to the histologic diagnosis of malignancy.

Treatment for menopausal symptoms and having health insurance were associated with a lower prevalence of falls among Brazilian women.

Objectives: Brazil has an aging population. This study aims to raise awareness of the prevalence and factors associated with falls among Brazilian women.

Study Design: Cross-sectional study with 622 women over 50 years of age was conducted between 05/10/11 and 10/31/11 in the city of Campinas/São Paulo/Brazil in the form of a population survey.

Validation of the Portuguese version of the quality of life questionnaire of the European foundation for osteoporosis (QUALEFFO-41) in Brazilian women with postmenopausal osteoporosis with vertebral fracture.

To validate the Portuguese version of the quality of life questionnaire of the European foundation for osteoporosis (QUALEFFO-41) in Brazilian women with osteoporotic vertebral fractures (VF). A questionnaire validation study of 86 postmenopausal women was conducted. Women were divided into two groups: 43 in a group with VF and 43 in a group without osteoporosis, age-matched (±3 years).

Factors associated with osteoporosis in Brazilian women: a population-based household survey.

Unlabelled: The aging of Brazilian population has been well-documented. A longer time since menopause, poor self-perception of health, and having arthrosis and balance problems are factors associated with postmenopausal osteoporosis. Poor self-perception of health, menopausal treatment with natural remedies, smoking, and decreased functional capacity are associated with early onset of the disease.

Factors associated with self-perception of health among Brazilian women 50 years or older: a population-based study.

Objective: The aim of this study was to evaluate factors associated with self-perception of health among women 50 years or older living in a Brazilian city.

Methods: A cross-sectional, population-based study was conducted using self-reported data from a household survey carried out in a sample of 622 women 50 years or older. Sociodemographic and clinical factors associated with the women's perception of their own health (very good, good, fair, poor, or very poor) were assessed.