Impact of dispersion media and carrier type on spray-dried proliposome powder formulations loaded with beclomethasone dipropionate for their pulmonary drug delivery via a next generation impactor.

Drug delivery via aerosolization for localized and systemic effect is a non-invasive approach to achieving pulmonary targeting. The aim of this study was to prepare spray-dried proliposome (SDP) powder formulations to produce carrier particles for superior aerosolization performance, assessed via a next generation impactor (NGI) in combination with a dry powder inhaler. SDP powder formulations (F1-F10) were prepared using a spray dryer, employing five different types of lactose carriers (Lactose monohydrate (LMH), lactose microfine (LMF), lactose 003, lactose 220 and lactose 300) and two different dispersion media.

A forecasting model approach of sustainable electricity management by developing adaptive neuro-fuzzy inference system.

With an exponential industrial growth, an accurate demand forecasting of energy is of prime importance for strategic decision-making and new power policies regarding generation and distribution in the power sector. This is a great impediment in economic development as well as shattering people's daily life. Hence, forecasting of energy demand in emerging markets is one of the most important policy tool used by decision-makers all over the world.