Radiotherapy-Associated Paraneoplastic Pemphigus and Its Complications in a Patient with Nasopharyngeal Carcinoma.

Unlabelled: Paraneoplastic pemphigus arising in association with non-haematological cancers is extremely rare, and there are no reported cases of a patient developing this in the setting of nasopharyngeal carcinoma and only 2 reported cases of patients developing this in response to radiotherapy. Here, we present the case of a patient who developed radiotherapy-associated paraneoplastic pemphigus in the setting of nasopharyngeal carcinoma and who then developed multiple complications.

Learning Points: Paraneoplastic pemphigus has a remarkably similar clinical picture to other dermatologic diseases (for example, pemphigus vulgaris), and therefore, it is easy to miss the diagnosis.