Publications by Aamir Ali Kharl

Publications by authors named "Aamir Ali Kharl"

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Synthesis, structure and acetylcholinesterase inhibition activity of new diarylpyrazoles.

Mehwash Zia Shahid Hameed Humaira Nadeem Aamir Ali Kharl Necmi Dege

Bioorg Chem

April 2022

A variety of diarylpyrazole derivatives III-VI were synthesized and structurally characterized using FTIR, H and C NMR spectroscopy, and in case of compound VIb by X-ray single crystal analysis. The in vitro biological studies revealed that seven of the diarylpyrazole derivatives IIIa, IIIb, IIId, IIIe, IVa, IVb and IVd are highly potent inhibitors of acetylcholinesterase enzyme with IC values of 0.48 ± 0.

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