A Comparative Study of Blood Loss With and Without Infusion of Tranexamic Acid in Total Knee Replacement.

Introduction: Total knee replacement (TKR) is associated with significant blood loss in intra- and postoperative periods. This trial was designed to determine the efficacy of tranexamic acid (TXA) in the reduction of perioperative blood loss and the need for blood transfusion in patients undergoing primary TKR.

Materials And Methods: This study was performed at a tertiary care institute with 30 cases of primary unilateral TKR.