Bivariate correlation coefficients in family-type clustered studies.

We propose a unified approach based on a bivariate linear mixed effects model to estimate three types of bivariate correlation coefficients (BCCs), as well as the associated variances between two quantitative variables in cross-sectional data from a family-type clustered design. These BCCs are defined at different levels of experimental units including clusters (e.g.

[The osteocondensing variety of multiple myeloma. Review of the literature and description of a case].

A case of IgG myeloma with eburnation of the femoral and ileoischiopubic bones is described. A review of the literature confirmed the rarity of osteosclerotic myeloma, especially if other possible causes of bone eburnation or the typical contemporary existence of osteolysis are excluded. The hypothesis that osteosclerotic myeloma may constitute an autonomous form of the disease, probably related to the type and/or extent of the proliferating bone is discussed.

[Streptococcal seroepidemiology: comparison of 3 methods].

Streptococcal antibodies survey in adult population. In a series of 1609 hospitalized adult patients, without symptoms of acute or chronic streptococcal rheumatism, the level of antistreptococcal antibodies was measured, using three technical methods: the traditional one, i.e.

[Ceftriaxone, a long-acting cephalosporin. Microbiological, kinetic and clinical study].

Ceftriaxone effectively inhibited 332 out of 452 (73.45%) bacterial strains in vitro tests. 291 out of 365 (79.

[Piperacillin: microbiological and clinical studies].

A microbiological and clinical study of the action of piperacillin is presented. The drug showed an excellent in vitro antibacterial action on gram positive and gram negative microorganisms. Its in vitro action on Ps.

[Microbiological, kinetic and clinical study on a new cephamycin: cefotetan].

Microbiological, kinetic and clinical studies were conducted on a new cephamycin, cephotetan. In vitro the antibiotic was found to be very effective against all strains tested. It had a particularly strong action against Gram negative bacteria too.

[Lymphocytic and lymphocytoactive components in the etiopathogenic mechanisms of systemic lupus erythematosus. An analysis of the literature].

Lymphocyte populations play an important role in the mechanism of autoantibody induction, mainly of antinuclear ones, in such collagen diseases as S.L.E.

[Aerobic bacterial flora in cutaneous lesions and in venous catheters of severely burned patients].

Bearing in mind the complexity of the topic and its variability owing to the progress made in antibiotic management, and the development of many concepts concerning the pathogenesis and biochemistry of major burns, the already massive literature is supplemented by the addition of relatively recent data to enable comparisons to be made with regard to the quality and frequency of isolation of the bacterial flora observed in such patients, and above all their sensitivity to currently employed antibiotics. The investigation was conducted on patients admitted to the Turin CTO Major Burns Centre between 1972 and 1977. Initially (1972-1975), a microbiological examination was made of purulent secretions from wounds.

[Behavior of complement factors and plasma proteins in burns].

The behaviour of three complement components (C3, C4 and C3 activator), alpha 1, alpha 2, IgA, IgG, IgM, total proteins, and gamma globulins was followed 114 patients at the C.T.O.

[Streptococcus antibodies in various population groups with no apparent signs of streptococcal infection. Sero-epidemiological evaluation].

ASO- and streptozyme (STZ) antibodies were evaluated in about 2000 subjects: apparently healthy persons, persons in hospital, members of the armed forces, puerperae and their newborns. STZ antigen was found to be more sensitive than ASO; statistically much higher than STZ- and ASO+. The results were coincident (75%-90%) in subjects with normal antibody levels and those with "pathological" titres.

[Chronic hepatitis caused by B virus (HBV)].

Following a short review of the viruses underlying viral hepatitis and those which, as a secondary factory in the clinical picture, may cause fleeting liver damge, the subdivision of chronic hepatitis conditions on histopathological bases is described. Particular attention is paid to pathogenesis, with a study of the elimination of B virus, correlated to particular histopathological types. A series of 27 PCH and 49 ACH cases is reported.

[Anomalous immunoelectrophoretic behavior of ceruloplasmin in severely burned patients].

Laurell's two-dimensional technique was employed in a study of the immunoelectrophoretic behaviour of caeruloplasmin in 10 major burn cases. A double peak was noted throughout the entire course. The second peak disappeared on recovery whereas it persisted and was well marked in the case of those who died.

[Coagulation disorders due to burns. Disseminated intravascular coagulation (DIC) and its possible prevention].

Coagulation data were studied in 77 patients with severe burns divided into two groups (A, 45 cases, and B, 32 cases). Increased PDF, platelet deficiency, enhanced fibrinogen turnover, and paracoagulation tests showing disseminated intravascular coagulation were frequent in both groups. Platelet deficiency was significantly more frequent in group A (64.

[Histopathology of the liver in patients with severe burns. Preliminary biopsy study].

Liver histobiopsy was carried out in 21 patients with burns of from 25 to 75 percent, between the 2nd and 125th day following trauma. The most frequent type of lesion encountered was albuminoid degeneration and hydropic ballooning of the cytoplasm to the point that the parenchyma assumed a "vegetable" appearance. No steatosis intervenes until the 6th-8th day after the burn and where it was not present previously, is a sign that the patient's condition is worsening.

[Serum enzyme picture in major burns].

Serum GOT, GPT, LDH, CHE, MDH, SDH, PK, GLDM, LAP and amylase levels and serum ammonia were determined in 49 major burn cases with 2nd and 3rd degree lesions covering 25% to 80% of the body surface. GOT, GPT, LDH, CHE and gamma-GT have above normal in all cases. Limited and inconsistent movements were noted for the remaining enzymes.