Specific Features of TLR4 Expression in Structural Elements of Placenta in Patients with Preeclampsia.

We studied the expression of TLR4 (Toll-like receptor 4) in the syncytiotrophoblast and vascular endothelial cells of terminal and stem placental villi in severe preeclampsia and normal pregnancy. In women of both groups, the expression of TLR4 was higher in the syncytiotrophoblast that in placental endothelial cells. In patients with severe preeclampsia, TLR4 expression in endothelial cells of terminal villi was 1.

Expression of adhesion molecules and cyclin d1 in cells of solid-pseudopapillary tumors of the pancreas.

Disturbances in the expression of cell adhesion molecules in solid-pseudopapillary tumor cells were detected by immunohistochemical methods. Positive reaction to E-cadherin, catenins, and overexpression of cyclin D1 were found; these changes reflect peculiarities of morphological structure and biological behavior of the studied neoplasms.

Morphological changes in the implantation zone of Prolen and Esfil reticular endoprostheses.

Comparative histological and electron microscopic study of tissues in the zone of implantation of polypropylene endoprostheses Prolen and Esfil was carried out in mice. Implantation of a reticular endoprosthesis Esfil was associated with a more pronounced infiltration with neutrophilic granulocytes, macrophages, and lymphocytes. Both nets were characterized by pronounced integration in the adjacent tissues in the implantation zone and can be recommended for clinical use.