Inhibition of protein kinase C (PKC) response of voltage-gated calcium (Cav)2.2 channels expressed in Xenopus oocytes by Cavβ subunits.

Cav2.2 channels are a substrate for phosphorylation by protein kinase C (PKC) isozymes. The contribution of Cavβ, an auxiliary subunit of these channels, in the PKC modulation was studied.

Antibody-dependent cell-mediated antibacterial activity: K lymphocytes, monocytes, and granulocytes are effective against shigella.

Normal human peripheral blood lymphocytes, monocytes, and granulocytes decreased the viability of Shigella flexneri in vitro in cooperation with heat-inactivated rabbit hyperimmune anti-shigella antisera. Purified K and T lymphocyte populations used before the removal of Fc receptor-bearing cells were effective in this antibody-dependent complement-free system. In contrast, B lymphocytes and T lymphocytes from which Fc receptor-bearing cells were removed exhibited no activity.