Publications by authors named "A-Lei Feng"
Repeated postoperative adjuvant TACE after curative hepatectomy improves outcomes of patients with HCC.
Minim Invasive Ther Allied Technol
June 2021
Article Synopsis
- The study aimed to investigate how postoperative adjuvant transcatheter arterial chemoembolization (TACE) impacts the recurrence of liver cancer (HCC) after surgery.
- Researchers analyzed data from 118 HCC patients who either had surgery followed by TACE or surgery alone between 2011 and 2013.
- Results showed that patients receiving two TACE treatments had a significantly higher three-year relapse-free survival rate (73.0%) compared to those getting one treatment (55.0%) or those with surgery alone (29.3%), indicating that TACE may help reduce tumor recurrence after surgery.
Objective: To make an informed choice of chemotherapy drugs according to the oncogene mRNA expression and to explore whether it could increase the survival rate of patients.
Patients And Methods: The study retrospectively analyzed 36 cases of nonsurgical esophageal squamous cell carcinoma patients treated at the Center for Oncology of Shandong Provincial Hospital from December 1, 2010, to November 1, 2013. Intensity-modulated radiation therapy was used for the treatment with a conventional radiotherapy dose of 60-66 Gy.
Background: T-helper (Th) 22 and Th17 cells are implicated in the pathogenesis of autoimmune diseases. The roles of Th22 cells in the pathophysiology of rheumatoid arthritis (RA) remain unsettled.
Materials And Methods: CD4(+)IFNγ(-)IL17(-)IL-22(+) T cells (Th22 cells), CD4(+)IFNγ(-)IL-22(-)IL17(+) T cells (pure Th17 cells), CD4(+)IL17(+) T cells (Th17 cells), and CD4(+)IFNγ(+) T cells (Th1 cells) in RA, osteoarthritis patients, and healthy controls were examined by flow cytometry.
The chemokine receptor CCR4 is preferentially expressed on certain immune cells and some hematological tumor cells, which play pivotal roles in suppression of host immune response. However, the reasons for the upmodulation of CCR4 and its immune functions in solid tumors remain unclear. Herein, we aimed to determine the expression profiles of CCR4 in gastric cancer cells and its role in regulating antitumor immunity.
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