Publications by authors named "A-L Fauchais"

Pre-eclampsia prevention represents a major public health issue, as this vasculo-placental disorder generates a great burden of foeto-maternal morbi-mortality. Aspirin has proved its efficacy in primary and secondary pre-eclampsia prevention, especially when it is given at 150mg per day bedtime before 15 weeks of gestation to high-risk women. In the English trial ASPRE, high-risk women were identified by an algorithm taking into account angiogenic biomarkers ascertained at the end of first trimester of pregnancy.

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Objective: We investigated the development of giant cell arteritis (GCA) in patients with prior diagnoses of isolated polymyalgia rheumatica and/or peripheral arthritis (PMR/PA), and the potentially relevant characteristics of both illnesses in such patients.

Methods: We retrospectively compared the features of 67 patients at the onset of PMR/PA, and their outcomes, to those of a random group of 65 patients with PMR/PA who did not develop late GCA. We also compared the features and outcomes of patients with late GCA to those of a random sample of patients with more usual GCA (65 with concurrent PMR/PA and 65 without).

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Introduction: Upper digestive symptoms may be present in up to 50% of patients with primary Sjögren syndrome (pSS). We report a retrospective cohort of gastroparesis in a population of pSS presenting unexplained dyspepsia. Delayed gastric emptying was defined by a gastric emptying time above 113min or by a retention percentage at 4h more than 10% on scintigraphy.

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Article Synopsis
  • - The study aimed to identify risk factors for permanent visual loss (PVL) in patients diagnosed with giant cell arteritis (GCA) over nearly 40 years, analyzing clinical and laboratory data from 339 patients.
  • - Key predictors for increased risk of PVL included older age, previous transient visual symptoms, and jaw claudication, while fever and rheumatic symptoms were associated with a significantly lower risk of visual loss.
  • - The findings indicate that clinical observations are crucial for estimating visual ischemic risk in GCA patients, emphasizing the necessity of prompt glucocorticoid treatment, as no patients were found to be entirely free of risk for visual loss.
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