Publications by authors named "A van der Kolk"
Purpose: Currently, maxillary sinus floor (SF) elevation is based on off-the-shelf allogeneic, xenogeneic or synthetic bone augmentation materials (BAM) that are implanted via an open lateral sinus wall approach (OSFE). However, this invasive method is associated with postoperative complications caused by an inadequate blood supply of the alveolar ridge. Balloon-assisted procedures are minimal invasive alternatives with lower complication rates.
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- Platelet-rich fibrin (PRF) is made from a patient's own blood and is used in dental procedures to enhance bone healing and stability when mixed with bone grafts.
- A study at the University Hospital Innsbruck analyzed the effectiveness of PRF in preventing vertical bone loss after dental implants, involving 362 implants in 170 patients between 2018 and 2021.
- Results showed that PRF use was linked to reduced vertical bone loss (> 1 mm) but did not significantly affect the number of lost implants or type of augmentation, indicating it could improve graft stability in oral implant procedures.
This article is an abridged version of the updated AWMF mould guideline "Medical clinical diagnostics in case of indoor mould exposure - Update 2023", presented in July 2023 by the German Society of Hygiene, Environmental Medicine and Preventive Medicine (Gesellschaft für Hygiene, Umweltmedizin und Präventivmedizin, GHUP), in collaboration with German and Austrian scientific medical societies, and experts. Indoor mould growth is a potential health risk, even if a quantitative and/or causal relationship between the occurrence of individual mould species and health problems has yet to be established. There is no evidence for a causal relationship between moisture/mould damage and human diseases, mainly because of the ubiquitous presence of fungi and hitherto inadequate diagnostic methods.
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- - Diagnosing Buruli ulcer (BU) is challenging due to limited access to a reliable detection method, but researchers are exploring the use of volatile organic compounds (VOCs) emitted by the bacteria Mycobacterium ulcerans for diagnosis.
- - The study involved two phases: a discovery phase where specific VOCs produced by M. ulcerans were identified, and a validation phase that tested these VOCs on clinical samples from ulcer patients in the Democratic Republic of Congo.
- - Analysis of the headspace samples revealed 24 distinct VOC fragments associated with M. ulcerans, with methylcyclohexane emerging as the most effective compound, although further research is needed to confirm their potential as diagnostic biomarkers.
Background And Aims: Immune checkpoint inhibitors (ICIs) revolutionized cancer treatment. However, ICIs may increase the immune response to non-tumor cells, possibly resulting in increased arterial inflammation, raising the risk of atherosclerotic events. Nevertheless, malignancies may induce a pro-inflammatory state and the association between ICIs and arterial inflammation remains to be clarified.
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