Publications by authors named "A van der Kemp"
Article Synopsis
- Effective self-management is crucial for older adults, with or without TBI, to sustain health and independence, and self-regulation strategies can enhance this.
- A study involving 41 older adults tested a specific intervention (MCII) aimed at preventing falls, assessing aspects like treatment adherence and participant feedback.
- Results showed behavior changes across participants, with those without TBI finding the MCII protocol more acceptable and feasible; however, those with TBI required more adjustments to the treatment, indicating room for improvement in personalized care.
Coenzyme Q10 (CoQ10) is a powerful antioxidant. However, the poor water solubility and low bioavailability still remain challenges for its application. An embedded delivery system of CoQ10 based on whey protein concentrate (WPC) and polymerized whey protein concentrate (PWPC) was prepared, and the physicochemical properties, antioxidant capacity and bioavailability were characterized in this study.
View Article and Find Full Text PDFMachine learning approaches including deep learning models have shown promising performance in the automatic detection of Parkinson's disease. These approaches rely on different types of data with voice recordings being the most used due to the convenient and non-invasive nature of data acquisition. Our group has successfully developed a novel approach that uses convolutional neural network with transfer learning to analyze spectrogram images of the sustained vowel /a/ to identify people with Parkinson's disease.
View Article and Find Full Text PDFArticle Synopsis
- The 3-chymotrypsin-like protease (3CL-PR) of SARS-CoV-2 is essential for virus replication and is targeted by the COVID-19 drug Paxlovid, making it important for understanding its catalytic behavior.
- Research indicates that the activity of 3CL-PR is pH-dependent, with specific acidic and basic groups necessary for optimal enzymatic function, suggesting a neutral catalytic dyad involving cysteine and histidine.
- Kinetic studies reveal faster rates in certain conditions, highlighting the influence of the active form of the enzyme, and a full catalytic mechanism for 3CL-PR is proposed based on these findings.
Background: Nursing curriculum lacks content addressing care of transgender (trans) individuals. Gender diversity in health care education must be enhanced to prevent discrimination and systemic biases.
Method: A shared session between pediatric and medical-surgical courses using an interactive video simulation facilitated student preparation to provide inclusive care for trans surgical clients.