Dynamic emotion intensity estimation from physiological signals facilitating interpretation via appraisal theory.

Appraisal models, such as the Scherer's Component Process Model (CPM), represent an elegant framework for the interpretation of emotion processes, advocating for computational models that capture emotion dynamics. Today's emotion recognition research, however, typically classifies discrete qualities or categorised dimensions, neglecting the dynamic nature of emotional processes and thus limiting interpretability based on appraisal theory. In our research, we estimate emotion intensity from multiple physiological features associated to the CPM's neurophysiological component using dynamical models with the aim of bringing insights into the relationship between physiological dynamics and perceived emotion intensity.

A first-in-human study of JNJ-70218902, a bispecific T-cell-redirecting antibody against TMEFF2 in metastatic castration-resistant prostate cancer.

Background: Metastatic castration-resistant prostate cancer (mCRPC) has a poor prognosis, necessitating the investigation of novel treatments and targets. This study evaluated JNJ-70218902 (JNJ-902), a T-cell redirector targeting transmembrane protein with epidermal growth factor-like and 2 follistatin-like domains 2 (TMEFF2) and cluster of differentiation 3, in mCRPC.

Patients And Methods: Patients who had measurable/evaluable mCRPC after at least one novel androgen receptor-targeted therapy or chemotherapy were eligible.

An agar medium-based method for screening somatic incompatibility in Agaricus bisporus.

To visualize the nonself recognition reaction in the cultivated mushroom Agaricus bisporus, we developed a method using the azo dye Evans blue. The use of Evans blue highlights dead mycelial sections, which are produced following nonself recognition in the interaction zone between two individuals. This method can differentiate between distinct heterokaryons, as well as between closely related heterokaryons constructed from siblings.

Conversion of Lignocellulosic Biomass Into Valuable Feed for Ruminants Using White Rot Fungi.

White rot fungi can degrade lignin and improve the nutritional value of highly lignified biomass for ruminants. We screened for excellent fungi-biomass combinations by investigating the improvement of digestibility of wheat straw, barley straw, oat straw, rapeseed straw, miscanthus, new reed, spent reed from thatched roofs, and cocoa shells after colonisation by Ceriporiopsis subvermispora (CS), Lentinula edodes (LE), and Pleurotus eryngii (PE) (indicated by increased in vitro gas production [IVGP]). First, growth was evaluated for three fungi on all types of biomass, over a period of 17 days in race tubes.

Photonic Quantum State Tomography Using Free Electrons.

The tomography of photonic quantum states is key in quantum optics, impacting quantum sensing, computing, and communication. Conventional detectors are limited in their temporal and spatial resolution, hampering high-rate quantum communication and local addressing of photonic circuits. Here, we propose to utilize free electron-photon interactions for quantum state tomography, introducing electron homodyne detection with potential for femtosecond-temporal and nanometer-spatial resolutions.