Publications by authors named "A de Ruiter"

Article Synopsis
  • Lowering viral load during pregnancy is crucial to reduce the risk of HIV-1 vertical transmission, and minimizing drug exposure to the fetus is a key principle.
  • While Dolutegravir/lamivudine (DTG/3TC) shows high effectiveness and safety in non-pregnant individuals, its initial use in pregnant HIV-1 patients is not recommended due to limited data.
  • Recent studies suggest that DTG/3TC may be effective and safe for pregnant individuals, showing high rates of viral suppression and no increased risk of neural tube defects, making it a potentially preferable option to more complex regimens.
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HIV incidence among transgender women remains high and disproportionately impacts young, Black, and Latina transgender women. Data on preferred PrEP modalities among this population are limited. Participants in The LITE Cohort completed a survey module on PrEP modality preferences during 24-month study visits.

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Background: The prevention of perinatal human immunodeficiency virus (HIV) transmission depends on the safe and effective use of antiretroviral therapy (ART). Simplifying treatment reduces drug exposure for both mother and child. We evaluated the safety and efficacy of dolutegravir (DTG) plus lamivudine (3TC) for antiretroviral-naive pregnant women with HIV.

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: To determine the rate of benign pathology in cT1 tumors following partial nephrectomy in the Netherlands, thereby evaluating the rate of overtreatment. Data were collected from a nationwide database containing histopathology of resected renal tissue from 2014 to 2022. Patients who underwent partial nephrectomy for suspected RCC staged T1a-b were extracted for analysis.

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The 275th ENMC workshop on the diagnosis and management of seronegative myasthenia gravis (SNMG) was held on February 9-11, 2024. The participants included experts in the field of adult and pediatric MG together with patient representatives. This workshop aimed to redefine SNMG in view of recent diagnostic and therapeutic updates and to identify patient unmet needs.

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