Publications by authors named "A de La Rochefordiere"

Purpose: The influence of human immunodeficiency virus (HIV) infection on clinical outcomes in patients receiving (chemo)radiation therapy (RT) for squamous cell carcinoma of the anus (SCCA) is debated. The objective of this study was to compare efficacy and safety according to HIV status in patients with SCCA treated with C/RT.

Methods And Materials: Between January 2015 and April 2020, 488 patients with a known HIV status (17.

View Article and Find Full Text PDF

Objective: The treatment of early-stage cervical cancer (CC) is primarily based on surgery. Adjuvant (chemo)radiotherapy can be necessary in presence of risk factors for relapse (tumor size, deep stromal invasion, lymphovascular space invasion (LVSI), positive margins, parametrial or lymph node involvement), increasing the risk of treatment toxicity. Preoperative brachytherapy can reduce tumor extension before surgery, potentially limiting the need for adjuvant radiotherapy.

View Article and Find Full Text PDF
Article Synopsis
  • Cervical cancer is mostly caused by a virus called HPV, and people with advanced cancer have a higher chance of getting worse after treatment.
  • Scientists studied blood samples from 94 patients to see if a specific part of HPV in the blood could help predict if their cancer would come back.
  • They found that when the HPV DNA was cleared from the blood after treatment, patients had a better chance of staying cancer-free, while those who still had HPV DNA were more likely to relapse within about 10 months.
View Article and Find Full Text PDF

Background: Cervical cancer (CC) remains a leading cause of gynaecological cancer-related mortality world wide and constitutes the third most common malignancy in women. The RAIDs consortium (http://www.raids-fp7.

View Article and Find Full Text PDF