Publications by authors named "A de Heredia"

The corrosion rates of carbon steel and galvanized steel according to the ISO 9223 standard, the effect of pollutant contamination and atmospheric aggressiveness under high rainfall conditions in the Chocó department were studied. Carbon and galvanized steel samples, chloride, and sulfur collectors were exposed in three atmospheric stations in three strategic positions covering the Colombian Pacific: Quibdó, Andagoya and Bahía Solano, for different exposure periods (up to 18 months). The structural-micro characterization of corrosion products was evaluated via X-ray diffraction (XRD), Raman spectroscopy and scanning electron microscopy coupled with energy-dispersive X-ray spectroscopy SEM-EDS.

View Article and Find Full Text PDF

Antiretroviral therapy (ART) improves the quality of life for those living with the human immunodeficiency virus type one (HIV-1). However, poor compliance reduces ART effectiveness and leads to immune compromise, viral mutations, and disease co-morbidities. Here we develop a drug formulation in which a lipid-based nanoparticle (LBNP) carrying rilpivirine (RPV) is decorated with the C-C chemokine receptor type 5 (CCR5) targeting peptide.

View Article and Find Full Text PDF

In view of the increasing demand for plant-based protein alternatives, along with the increased protein requirements of older adults, the formulation of new food concepts based on protein-rich ingredients from legumes or pseudo-cereals seems a promising approach. Previous studies have found that solid-state fermentation can improve the nutritional value and digestibility of plant-based commodities; however, scarce evidence exists regarding the effect on prebiotic potential. This study aimed to compare the effect of fermented and unfermented quinoa and lentil flours on the colonic microbiota, as well as that of new food prototypes (gels and breads) made with the flours.

View Article and Find Full Text PDF

: The increase in the older adult population worldwide and the need to switch to vegetal-origin protein consumption for environmental sustainability point to legumes and pseudocereals as alternative ingredients in new food formulations. This study aimed to assess the impact of food structure and fungal fermentation on the digestibility of new food prototypes made with quinoa and/or lentil flours addressed to older adults. : Four gels and six breads were elaborated and subjected to mechanical analysis and simulated gastrointestinal in vitro digestion.

View Article and Find Full Text PDF

Asymptomatic IgM gammopathy encompasses IgM monoclonal gammopathy of undetermined significance (MGUS) and asymptomatic Waldenström macroglobulinemia (AWM), both having a risk of progression to symptomatic disease. Here, we assessed the risk of progression and the mortality of 956 patients with asymptomatic IgM gammopathy across 25 Spanish centers. After a median follow-up of 5.

View Article and Find Full Text PDF