Sternoclavicular Joint Reconstruction Using a Hamstring and Cadaveric Fibular Cortical Allograft: A Case Report.

Case: A 49-year-old woman with sternoclavicular insufficiency following medial clavicle resection underwent sternoclavicular joint reconstruction using a hamstring allograft and a cadaveric fibular cortical allograft. After 4 months of follow-up, the patient was pain-free, with radiographic evidence of graft incorporation by 8 months.

Conclusion: Medial clavicle resection is a rare procedure with broad indications.

Impact of Mental Health Disorders on Outcomes Following Shoulder Arthroplasty.

Background: There is conflicting evidence on the impact of mental health on postoperative outcomes following total joint arthroplasty. Specific to shoulder arthroplasty there is a lack of data investigating the correlation between mental health and surgical outcomes. Most studies have focused on patient-reported outcome measures, while few have explored objective clinical outcomes.

"MoSpec": A customized and integrated system for model development, verification and validation.

Background And Objective: The growing availability of patient data from several clinical settings, fueled by advanced analysis systems and new diagnostics, presents a unique opportunity. These data can be used to understand disease progression and predict future outcomes. However, analysing this vast amount of data requires collaboration between physicians and experts from diverse fields like mathematics and engineering.

Multianalytical investigation reveals psychotropic substances in a ptolemaic Egyptian vase.

This study presents a comprehensive multimodal analytical study of an Egyptian ritual Bes-vase, of the 2nd century BCE employing cutting-edge proteomics, metabolomics, genetics techniques, and synchrotron radiation-based Fourier Transformed Infrared microSpectroscopy (SR µ-FTIR) to characterize organic residues of its content. We successfully identified the presence of various functional, bioactive, psychotropic, and medicinal substances, shedding light on the diverse components of a liquid concoction used for ritual practices in Ptolemaic Egypt. Using LC-MS/MS with a new methodological approach, we identified key proteins and metabolites, enabling the identification of botanical sources, confirmed by genetic sequences.

Recent Advances in Artificial Intelligence to Improve Immunotherapy and the Use of Digital Twins to Identify Prognosis of Patients with Solid Tumors.

To date, the public health system has been impacted by the increasing costs of many diagnostic and therapeutic pathways due to limited resources. At the same time, we are constantly seeking to improve these paths through approaches aimed at personalized medicine. To achieve the required levels of diagnostic and therapeutic precision, it is necessary to integrate data from different sources and simulation platforms.