Publications by authors named "A Zuppiroli"
LDL-cholesterol target levels achievement in high-risk patients: An (un)expected gender bias.
Nutr Metab Cardiovasc Dis
January 2024
Background And Aims: Lowering low-density lipoprotein cholesterol (LDL-C) is the cornerstone of cardiovascular disease prevention. Collection of epidemiological data is crucial for monitoring healthcare appropriateness. This analysis aimed to evaluate the proportion of high-risk patients who achieved guidelines recommended LDL-C goal, and explore the predictors of therapeutic failure, with a focus on the role of gender.
View Article and Find Full Text PDFArticle Synopsis
- The study examined the effectiveness of three antiviral treatments for early COVID-19 (nirmatrelvir/ritonavir, molnupiravir, and remdesivir) among a large group of outpatient patients.
- 1,342 patients were analyzed, with high clinical recovery rates (96.9%) and a low hospitalization rate (2.6%), showing no significant differences in outcomes between the antiviral treatments.
- Vaccination status was important, as vaccinated patients had a lower risk of hospitalization or death compared to unvaccinated individuals.
Background: People who inject drugs (PWID) and homeless people represent now a large reservoir of Hepatitis C virus (HCV) infection. However, Hepatis C elimination programs can barely reach these subgroups of patients. We aimed to evaluate and compare the retention in care among these difficult-to-treat patients when managed for HCV in hospital or in an out-of-hospital setting.
View Article and Find Full Text PDF[Chronic diseases and risk of symptomatic COVID-19: results of a case-population study on a sample of patients in the Local Health Unit 'Toscana Centro' (Tuscany Region, Central Italy)].
Epidemiol Prev
January 2021
Article Synopsis
- - The study investigates the impact of chronic diseases on the risk of developing mild to symptomatic COVID-19 infections in the Toscana Centro region, where significant case numbers were reported during the pandemic.
- - It analyzes data from 1,840 confirmed cases, highlighting that older males and individuals with chronic conditions such as heart failure and psychiatric disorders are at a significantly higher risk of severe symptoms related to SARS-CoV-2.
- - Findings indicate that having a chronic disease increases a person's risk of symptomatic COVID-19 by 68%, emphasizing the need for further research on chronic illness factors in managing pandemic responses.