A study of some factors influencing the epidemiology of urinary schistosomiasis at Ifakara (Kilombero District, Morogoro Region, Tanzania).

Some factors influencing the epidemiology of urinary schistosomiasis were studied at Ifakara between 1978 and 1980. Ifakara is situated in the fertile plain of the Kilombero river in the south-eastern part of Tanzania. The overall prevalence of Schistosoma haematobium infection among primary school children (6-19 years) in the Ifakara agglomeration was 21% (730/3478).

Morphometric analysis of the capillary supply in skeletal muscles of trained and untrained subjects--its limitations in muscle biopsies.

Muscle fiber area, capillary density, and capillary to fiber ratio were determined in needle biopsy samples of M. vastus lateralis processed for electron microscopy from 9 untrained men (average VO2 max = 43.7 ml/min kg) and 5 well trained orienteers (VO2 max = 76.

Gamma-aminobutyric acid can both inhibit and facilitate dopamine release in the caudate nucleus of the rabbit.

Slices from rabbit caudate nucleus were preincubated with [3H]dopamine and then superfused and stimulated electrically. gamma-Aminobutyric acid (10-4) and 10(-3) mol/L increased both the basal and the stimulation-evoked overflow of tritium. The effects were not changed by picrotoxin and were only slightly reduced by bicuculline.

Pathways of dopamine metabolism in the rabbit caudate nucleus in vitro.

Slices of rabbit caudate nucleus were preincubated with 3H-dopamine and then superfused. 3H-dopamine and its metabolites were separated by column chromatography. The basal outflow of tritium consisted of 68% DOPAC, 21% OMDA metabolites (most of which was HVA), 6% dopamine and 5% MTA.

Interneurones are probably not involved in the presynaptic dopaminergic control of dopamine release in rabbit caudate nucleus.

Slices of rabbit caudate nucleus were preincubated with 3H-dopamine and then superfused. The influence of apomorphine and haloperidol on the overflow of tritium evoked by 20 mmol/l potassium was investigated in the presence and in the absence of tetrodotoxin. The potassium-evoked overflow was largely calcium-dependent and consisted mainly of 3H-dopamine.