Publications by authors named "A Zoppo"

Background: Metabolic dysfunction-associated Steatotic Liver Disease (MASLD) displays a worse prognosis in subjects with type 2 diabetes (T2D); effective treatments are, so far, scanty. Semaglutide showed efficacy in improving steatohepatitis. We longitudinally observed a MASLD cohort of T2D subjects starting semaglutide, to detect an improvement of non-invasive surrogates of steatosis and fibro-inflammatory liver involvement, evaluating the role of mild alcohol consumption.

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Background: Menopausal transition is a crucial step in the women's cardiovascular health, and the risk stratification in apparently health post-menopausal females has been rarely assessed. Heart ultrasonography, unusually performed in such subjects, would be able to detect initial signs of organ damage. We described the cardiovascular risk profile of non-diabetic post-menopausal women, evaluating how easily computed, biochemistry-derived scores were related to ultrasonographic measures of target organ damage.

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Article Synopsis
  • Spinocerebellar ataxia 38 (SCA38) is linked to mutations in the ELOVL5 gene, leading to reduced levels of docosahexaenoic acid (DHA), a crucial fatty acid, which negatively impacts patients' health.* -
  • A study involving 10 SCA38 patients showed that after 16 weeks of DHA supplementation, clinical improvements were significantly greater compared to a placebo group, and continued benefits were observed after 40 weeks of treatment.* -
  • The research indicated that DHA is a safe and effective treatment for SCA38, resulting in improved clinical symptoms and brain function without any reported side effects.*
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Background: Ultrasound (US)-elastography is a newly developed imaging technique for the reconstruction of tissue stiffness by measuring the degree of tissue's deformation in response to the application of an external force. This technique has previously been shown to be useful in the differential diagnosis between benign and malignant tumors.

Methods: The objective of this study was to assess the diagnostic accuracy of US-elastography in the differential diagnosis of thyroid cancer, using the cytologic/histopathologic analysis as the reference standard.

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