Publications by authors named "A Zittermann"

Purpose: It has been assumed that magnesium (Mg) status may interact with vitamin D status. We therefore aimed at investigating the association between Mg and vitamin D status in a large cohort of adult individuals with a high prevalence of deficient/insufficient vitamin D and Mg status.

Methods: We used data from the Ludwigshafen Risk and Cardiovascular Health Study (n = 2,286) to analyze differences according to serum Mg status in circulating 25-hydroxyvitamin D [25(OH)D] (primary endpoint), 24,25-dihydroxyvitamin D [24,25(OH)D], vitamin D metabolite ratio and calcitriol, and odds ratios for deficient or insufficient 25(OH)D (secondary endpoints).

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  • * The study retrospectively compared outcomes of patients with coronary artery disease (CAD) and very low left ventricular function who received either CABG or LVAD, using statistical matching to analyze 168 pairs.
  • * Results indicated that while LVAD patients needed longer ventilation and ICU stays, they had lower rates of postoperative renal therapy and required less temporary mechanical support; however, CABG patients had significantly better mid-term survival rates compared to those receiving LVADs.
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Background: The SynCardia® temporary total artificial heart (TAH) serves as a mechanical circulatory support device for patients suffering from irreversible biventricular failure.

Methods: This retrospective study analyzed 196 consecutive patients who underwent TAH implantation at our center from 2001 to 2021. We assessed survival rates and all-cause mortality during TAH support, including survival post-heart transplantation.

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  • The study investigates outcomes of extracorporeal life support in patients with low-output syndrome following cardiac surgery, revealing high initial mortality rates and identifying significant risk factors for both short- and long-term survival.
  • Over 570 patients were analyzed, with findings that severe aortic valve issues and previous surgeries increased in-hospital mortality, while older age and severe mitral regurgitation predicted long-term mortality, particularly for those on insulin.
  • Despite poor overall outcomes, peripheral cannulation improved survival chances, and only about 32% of patients survived beyond ten years post-discharge, highlighting the need for targeted monitoring of high-risk patients.
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