Publications by authors named "A Ziman"
Article Synopsis
- Referral laboratories can create challenges for hospitals, including regulatory issues and delays in test results, especially when using "miscellaneous" order types.
- A new referral test request process was created, leading to the approval of 16 out of 27 new tests and transitioning 37 frequently ordered miscellaneous tests to discrete orders in the electronic health record.
- The uptake of these new orders was significant, averaging 64%, and result turnaround times improved by an average of 1.1 days.
Introduction: In response to the COVID-19 pandemic, we rapidly implemented a plasma coordination center, within two months, to support transfusion for two outpatient randomized controlled trials. The center design was based on an investigational drug services model and a Food and Drug Administration-compliant database to manage blood product inventory and trial safety.
Methods: A core investigational team adapted a cloud-based platform to randomize patient assignments and track inventory distribution of control plasma and high-titer COVID-19 convalescent plasma of different blood groups from 29 donor collection centers directly to blood banks serving 26 transfusion sites.
Article Synopsis
- Scientists found that as we get older, the way our DNA is organized in cells changes, especially in bone marrow cells called pro-B cells.
- These changes make some parts of DNA interact more with each other while others don’t connect as much anymore.
- A specific gene, Ebf1, moves to a different area in the DNA as we age, and when this gene is reduced, it makes the old cell features even more noticeable.