Substances of silver nanoparticles dialyzed through a 13 kDa membrane, synthesized in a medium of humic ligands modified with hydroquinone and 2-hydroxynaphthoquinone from PowHumus brown coal, specifically enhance the M2 properties of peritoneal macrophages due to inhibition of NO synthase and significant activation of arginase, thus enhancing anti-inflammatory properties of cells. In small, but effective concentrations, they do not have cytotoxic properties and do not contain pyrogenic impurities. The studied humates are able to influence the mechanisms of immune response formation and are an effective means for correcting inflammation and regeneration.
View Article and Find Full Text PDFThe current article describes the biological activity of new biomaterials combining the "green" properties of humic substances (HSs) and silver nanoparticles. The aim is to investigate the antioxidant activity (AOA) of HS matrices (macroligands) and AgNPs stabilized with humic macroligands (HS-AgNPs). The unique chemical feature of HSs makes them very promising ligands (matrices) for AgNP stabilization.
View Article and Find Full Text PDFAppl Microbiol Biotechnol
October 2022
Combinations of various strategic approaches to the suppression of methanogenesis and the formation of biogas with a simultaneous decrease in the ratio of methane in its composition were investigated. Introduction of methanogenesis suppressors such as redox derivatives of humic acids, potassium persulfate (KSO), possessing oxidizing and electron acceptor properties, enzyme hexahistidine-containing organophosphorus hydrolase with high lactonase activity and polypeptide antimicrobial agent bacitracin into the media with anaerobic consortia were studied. The effect of these substances was directed at various participants of the natural methanogenic consortium, as well as on the biochemical processes carried out by them.
View Article and Find Full Text PDFIzv Akad Nauk Ser Biol
November 2005
This work presents the data on the rate of utilization of phenols formed during lignin pyrolysis by micromycetes of the genera Trichoderma and Penicillium. Trichoderma strains utilized phenols at the concentration of liquid pyrolytic products of 0.5-1%, while representatives of Penicillium degraded over 50% phenols at the concentration of pyrolytic products of 2%.
View Article and Find Full Text PDFIzv Akad Nauk Ser Biol
August 2005
The data on the dynamics of the content and qualitative composition of intracellular alkanes in Paramecium caudatum Ehrenberg, 1838 cells feeding on bacteria with different levels of exposure to diesel oil are presented. The possibility of migration of alkanes from diesel oil along the trophic chain from bacteria to ciliates was demonstrated.
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