Association Between Dipeptidyl Peptidase-4 Inhibitor Use and Cognitive Functions, Brain-Derived Neurotrophic Factor, and Pentraxin-3 Levels in Patients With Type 2 Diabetes.

Background Diabetes mellitus is an important risk factor for dementia, Alzheimer's disease, and other neurodegenerative diseases. Recent findings have made the relationship between the inhibition of the dipeptidyl peptidase-4 (DPP-4) enzyme and cognitive functions an important research topic. Objective This study aimed to evaluate the association between DPP-4 inhibitor use and cognitive functions, serum brain-derived neurotrophic factor (BDNF), and pentraxin-3 (PTX-3) levels in patients with type 2 diabetes, compared with the patients who only use metformin treatment.

MEFV gene pathogenic variants: a risk factor for dysmenorrhea in the Turkish population.

Background/aim: The Mediterranean fever (MEFV) gene codes for protein pyrin, which is among the modulators of inflammasome activity in innate immune cells. It was suggested that there is a relation between MEFV variations and inflammatory diseases. The aim of this study was to investigate MEFV gene variations in the patients with primary dysmenorrhea.

Relationship of The Characteristic Imaging Findings of Breast Cancer with Molecular Subtypes in Young Women.

Background: The characteristic imaging findings of breast cancer in young women are not yet fully understood. It causes a delay in diagnosis by mixing with benign findings.

Objective: To evaluate the relationship between the imaging and histopathological features of breast cancer in women aged under 40 years.

The relationship between kinesiophobia and physical activity levels, gestational weight gain, and musculoskeletal pain in pregnant women.

The aim of this cross-sectional study was to investigate the effect of kinesiophobia on musculoskeletal pain, physical activity levels, and gestational weight gain in pregnant women. One hundred and sixty-three pregnant women participated in the study by completing a personal characteristics information form along with the Tampa Scale of Kinesiophobia, the Pregnancy Physical Activity Questionnaire, and the Cornell Musculoskeletal Discomfort Questionnaire. The results showed a weak negative correlation between total physical activity scores and Tampa Scale of Kinesiophobia scores ( = .