Publications by authors named "A Zentella-Dehesa"
Article Synopsis
- Type 2 diabetes is a significant public health issue in Mexico, with a multidisciplinary program, CAIPaDi, aimed at reducing complications through patient-centered care.
- Between 2013 and 2023, the program tracked various health indicators, showing significant improvements in diabetes control and a decrease in obesity rates among participants.
- The findings revealed low rates of acute events, no lower limb amputations, and a reduction in mental health issues, indicating the program's overall effectiveness in managing diabetes and improving patient outcomes.
Background: ESR1 is expressed by 60-70% of breast tumours. it's a good prognosis factor and the target of hormone therapy. Optimization of ESR1 reactivation therapy is currently ongoing.
View Article and Find Full Text PDFThe inhibitory effect of trastuzumab on BT474 triple‑positive breast cancer cell viability is reversed by the combination of progesterone and estradiol.
Oncol Lett
January 2024
Breast cancer expressing the estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor-2 (HER2) is known as triple-positive (TPBC). TPBC represents 9-11% of breast cancer cases worldwide and is a heterogeneous subtype. Notably, TPBC presents a therapeutic challenge due to the crosstalk between the hormonal (ER and PR) and HER2 pathways.
View Article and Find Full Text PDFThe cytotoxic activity of combinations of masticadienonic (AMD) or 3αOH-hydroxy-masticadienonic (3αOH-AMD) acids with cisplatin (CDDP) was evaluated against PC3 prostate and HCT116 colon cancer cell lines. Combinations A (half the IC value), B (IC value), and C (twice the IC value) were tested at a 1 : 1 ratio. All AMD plus CDDP combinations demonstrated increased cytotoxic effect, as determined by the sulforhodamine B test, in both cell types.
View Article and Find Full Text PDFBackground: Oral cancer has a high prevalence worldwide, and this disease is caused by genetic, immunological, and environmental factors. The main risk factors associated with oral cancer are smoking and alcohol.
Results: There are various strategies to reduce risk factors, including prevention programs as well as the consumption of an adequate diet that includes phytochemical compounds derived from cranberries ( A.