Publications by authors named "A Zakrzeska"
The aim of this study was to evaluate the effects of D-aspartic acid (DAA) supplementation during a simulated altitude protocol on the hormonal and hematological responses in athletes. We hypothesized that DAA supplementation would contribute to an increase in the luteinizing hormone (LH), free, and testosterone and a greater increase in hematological variables. Sixteen male boxers participated; they were randomly assigned to an experimental group (DAA) or a control group (C) and underwent 14 days of supplementation, 6 g/day of DAA.
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- The study assessed the therapeutic effects of chlorogenic acid (CGA) on rats with advanced alcoholic steatohepatitis induced by a high-fat diet and ethanol for 8 weeks.
- Ethanol-treated rats showed signs of liver damage including steatosis, inflammation, and upregulation of several harmful genes related to oxidative stress, inflammation, and fibrosis.
- CGA treatment significantly decreased detrimental gene expression and improved liver conditions, highlighting its potential as a protective and anti-inflammatory agent against alcoholic steatohepatitis.
We investigated the role of aldosterone (ALDO) in the development of arterial thrombosis in streptozotocin-induced diabetic rats. To evaluate the effect of endogenous ALDO, the rats underwent adrenalectomy (ADX). ADX reduced the development of arterial thrombosis.
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- A study investigated the effects of whey protein concentrate (WPC-80) on thrombosis development in rats, using two doses over varying durations (7, 14, or 21 days).
- Thrombus weight significantly decreased in rats supplemented with WPC-80 after 14 and 21 days, indicating a potential benefit of the protein on clot formation.
- Coagulation parameters and platelet counts showed minor variations across groups but lacked a clear trend, suggesting that further studies are necessary to fully understand these effects.
species that have been investigated so far display pharmacological activity mainly due to the presence of polyphenols. Recently, it was shown that polyphenol-rich extract from rhizome of (tormentil extract) affects the metabolism of arachidonic acid and exerts both anti-inflammatory and anti-oxidant activities, suggesting a possible effect on thrombosis. Accordingly, the aim of the study was to evaluate the effect of tormentil extract on haemostasis in a rat model of thrombosis.
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