Validating psychometric properties of generic quality-of-life instruments (WHOQOL-BREF (TW) and EQ-5D) among non-dialysis chronic kidney disease: Rasch and confirmatory factor analyses.

Background: Quality of life (QOL) is important for evaluating medical care outcomes. In chronic kidney disease (CKD) population, generic instruments, such as WHOQOL-BREF and EQ-5D, are commonly used for comparing various medical conditions for policy-making purposes. However, their psychometric properties have not yet been validated in non-dialysis CKD population.

Circulating tumour DNA in predicting and monitoring survival of patients with locally advanced rectal cancer undergoing multimodal treatment: long-term results from a prospective multicenter study.

Background: Neoadjuvant chemoradiotherapy (nCRT) is the standard for locally advanced rectal cancer (LARC). However, distant metastasis remains the primary cause of treatment failure. Early identification of high-risk individuals for personalized treatment may offer a solution.

The Relationship Between Parental Involvement and Adolescents' Cooperative Tendencies in China: The Mediating Role of Parent-Child Trust.

Does greater parental involvement lead to increased cooperation in their adolescent children? Are the effects of paternal and maternal involvement equivalent? In order to explore the above issues, this study conducted a questionnaire survey of 682 two-parent families to investigate the relationship between parental involvement and adolescents' cooperative tendencies and the mediating role of parent-child trust. The results show that paternal involvement directly predict adolescents' cooperative tendencies, while maternal involvement could not directly predict cooperative tendencies. In addition, parent-child trust mediates the relationship between parental involvement and adolescents' cooperative tendencies.