Antibiot Khimioter
February 2000
At present 10 to 30 per cent of the microbial strains from cancer patients are problem ones: oxacillin resistant strains of Staphylococcus aureus, coagulase negative strains of Staphylococcus spp., aminoglycoside resistant strains of Escherichia coli, 3rd generation cephalosporin resistant strains of Klebsiella spp. and fungi of Candida which requires development of more rational approaches to antibacterial chemotherapy and prophylaxis of infectious complications.
View Article and Find Full Text PDFFungal infection in oncologic hospitals is a serious threat for the patients that can undermine the results of the specific treatment of the main disease. Most frequently fungal infection is developing in localities naturally disseminated with microbial flora. The infection is usually mixed: bacterial/fungal and even fungal/fungal.
View Article and Find Full Text PDFCandida fungi, more than half of which are Candida albicans, are responsible for up to 28% of microflora contaminating the pathological material during infectious processes coursing in cancer patients. They may be isolated as a monoculture or in associations with bacteria, depending on the localization of the process. In both cases their pathogenetic significance is really great, which is confirmed by the efficacy of antimycotic therapy and prophylactic measures.
View Article and Find Full Text PDFThe investigation of the microflora of infectious complications in the urogenital tract of oncological patients showed that in spite of the similarity of the microbiotypes, the microflora of the infectious complications in the patients had marked differences. The causative agents in urological patients were mainly monocultures (69.9 per cent), whereas in gynecological patients they were mainly associations (67.
View Article and Find Full Text PDFSurgical threads containing cefazolin and cefoperazone were studied comparatively. Cefazolin was shown to incorporate into the structure of caproamide threads in an amount of 20 per cent by the thread weight while the cefoperazone incorporation amounted only to 3.7 per cent.
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