Publications by authors named "A Yoden"
Article Synopsis
- Endoscopic monitoring of ulcerative colitis (UC) in children is challenging due to the invasiveness of colonoscopies, making noninvasive methods like bowel wall thickness (BWT) measurement and fecal calprotectin (FC) testing important alternatives.
- A study of 40 pediatric UC patients evaluated the relationship between BWT, FC levels, and the Mayo endoscopic subscore (MES) to assess disease activity, revealing significant differences in these markers between low and moderate inflammation levels.
- Results indicated that adjusted BWT (saBWT) was more reliable than FC in identifying moderate colonic inflammation, suggesting that intestinal ultrasonography is a valuable tool for less invasive management of pediatric UC patients.
Background: Small bowel capsule endoscopy (SBCE) for Crohn's disease is useful; however, its use has some limitations, such as invasiveness when endoscopic assistance is required in patients who cannot swallow the capsule, and the burden of interpretation on a physician. In contrast, intestinal ultrasonography (IUS) is a non-invasive modality for children. The purpose of this study is to evaluate the accuracy of IUS for pediatric patients with established Crohn's disease.
View Article and Find Full Text PDFUnlabelled: Acute pancreatitis (AP) develops in approximately 2% of patients with the diagnosis of inflammatory bowel disease (IBD), but the characteristics and frequency of childhood-onset IBD-associated AP in Japan have not been studied. The present study aimed to clarify the characteristics of IBD-associated AP in Japan.
Methods: A nationwide survey of pediatric patients with IBD (age, <17 years) was conducted from December 2012 to March 2013 at 683 hospitals and medical centers in Japan.
Comprehensive Targeted Sequencing Identifies Monogenic Disorders in Patients With Early-onset Refractory Diarrhea.
J Pediatr Gastroenterol Nutr
September 2020
Objectives: Causes of early-onset refractory diarrhea include exudative diarrhea associated with very early-onset inflammatory bowel diseases, osmotic or secretory diarrhea, and protein-losing enteropathy. Monogenic disorders are included in these diseases, yet a comprehensive genetic analysis has not been fully established.
Methods: We established targeted gene panels covering all responsible genes for early-onset diarrhea.
Introduction: The incidence of early-onset inflammatory bowel disease is increasing in Japan.
Objective: This study aimed to analyze the treatment and progress of early-onset inflammatory bowel disease.
Methods: This prospective survey evaluated the data of 43 patients aged <8 years who were diagnosed with inflammatory bowel disease (IBD) from the time of diagnosis to 36 months after registration.