Publications by authors named "A Yamashiro"
[Designing T and T Relaxation Time Phantoms: From Material Selection to Measurement].
Nihon Hoshasen Gijutsu Gakkai Zasshi
January 2024
Article Synopsis
- The rising global incidence of diabetes raises concerns about chronic health issues, with diabetic nephropathy (DN) being a major cause of kidney failure.
- Podocyte injury in the glomerulus is a key factor in the development of DN, and research shows an increase in phosphorylated ERK (pERK), an active signaling molecule, in patients with DN.
- An immunohistochemical study revealed that podocytes in DN patients exhibit significantly higher pERK levels compared to healthy controls, indicating that ERK activation in podocytes may contribute to DN progression.
Article Synopsis
- A percutaneous kidney biopsy (PKB) is important for treating kidney diseases but has a risk of bleeding complications, which are influenced by factors like urinary N-acetyl-β-D-glucosaminidase (NAG) levels.
- In a study of 213 patients, about 25% experienced significant hemoglobin loss after undergoing PKB, and higher urinary NAG/Cr levels were linked to an increased risk of bleeding events.
- The study suggests that urinary NAG/Cr can predict not only the severity of kidney disease but also potential bleeding risks during and after the biopsy procedure.
Objectives: Several therapeutic agents have been developed and used for the clinical treatment of systemic lupus erythematosus (SLE). In cases where SLE is accompanied by severe organ failures, such as neuropsychiatric lupus erythematosus (NPSLE) and acute onset of lupus nephritis, the use of potent immunosuppressive drugs, such as cyclophosphamide, is necessary. However, potent immunosuppressive drugs are known to increase infection risks.
View Article and Find Full Text PDFBackground: As at June 14, 2023, the coronavirus disease 2019 (COVID-19) pandemic had affected more than 767 million people and caused more than 6.9 million deaths worldwide. This study aimed to clarify the lifestyle factors that influence the exacerbation of COVID-19 severity.
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