Publications by authors named "A Y Stepanenko"
Article Synopsis
- A patient with a serious deep sternal wound infection, severe heart failure, and sepsis was treated successfully despite significant health challenges.
- The surgical approach was complicated due to limited options for reconstructive surgery, highlighting the complexity of the case.
- The study also discusses methods for managing the patient's other health issues (comorbidities) in conjunction with the surgical treatment.
Article Synopsis
- The study compared long-term outcomes of minimally invasive coronary artery bypass grafting (MICS CABG) with traditional surgery through sternotomy, involving 158 patients for MICS and 150 for sternotomy.
- The results showed no significant differences in 5-year survival rates or freedom from adverse cardiac events between the two groups, but MICS CABG had lower rates of wound complications and shorter hospital stays.
- Overall, MICS CABG proved to be a safe and effective alternative, offering similar long-term results while providing benefits like faster recovery and reduced rehabilitation time, particularly for patients at higher risk of complications.
Article Synopsis
- Myval technology is a new balloon-expandable option for treating heart valve issues, emerging after the established Edwards system, and its usage is increasing despite some debated points.
- A thorough literature review covering studies from December 2016 to May 2024 showed Myval to be effective for native aortic stenosis with low mortality and complication rates, and its performance compares favorably to other devices.
- The findings also indicate that Myval is safe for various off-label uses, achieving high success rates across different heart valve procedures, although more extensive studies are needed to confirm these results.
Background: Older adults with type 2 diabetes mellitus (T2DM) or prediabetes are at increased risk of adverse changes in body composition, physical function, and aging-related biomarkers compared to those with normal glucose tolerance. Semaglutide is a glucagon-like peptide 1 receptor agonist that has been approved for T2DM and chronic weight management. Although semaglutide is effective for weight loss and T2DM management, its effects on lean body mass, physical function, and biomarkers of aging are understudied in older adults.
View Article and Find Full Text PDFRibosomal DNA (rDNA) contains highly conserved, specifically organized sequences encoding ribosomal RNAs (rRNAs) separated by variable non-transcribed intergenic spacers (NTSs) and is abundant in eukaryotic genomes. These characteristics make the rDNA an informative molecular target to study genome organization, molecular evolution, and phylogenetics. In this study, we characterized the 5S rDNA repeats in the greater duckweed , a species known for its small size, rapid growth, highly conserved genome organization, and low mutation rate.
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