Publications by authors named "A Y Ramdasi"

Aedes aegypti-borne viruses (i.e., dengue, chikungunya, and Zika) have become endemic to India, posing a severe threat to public health.

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Metagenomic analysis of and mosquitoes from diverse geographical regions of India revealed the presence of several insect viruses of human interest. Most abundant reads found in mosquitoes were of Phasi Charoen-like virus (PCLV), granulovirus (CfGV), Cell fusing agent virus (CFAV), and Wenzhou sobemo-like virus 4 (WSLV4), whereas WSLV4 and CfGV constituted the highest percentage of reads in viromes. Other reads that were of low percentage included Hubei mosquito virus 2 (HMV2), Porcine astrovirus 4 (PAstV4), and Wild Boar astrovirus (WBAstV).

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Article Synopsis
  • Mosquitoes, particularly Aedes aegypti, carry numerous insect-specific viruses (ISVs) that are usually not harmful to humans but can evolve into potential human pathogens.
  • A study conducted in Pune, India found that the Phasi Charoen-like virus (PCLV) comprised over 60% of mosquito viromes, showing high genetic similarity to Brazilian PCLV isolates.
  • The research also noted PCLV's presence in various mosquito life stages and highlighted the need for further investigation into how PCLV may affect the transmission of harmful viruses like dengue and chikungunya.
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With the changing hepatitis A epidemiology in India, focal viral outbreaks are being reported from different parts of the country. This study presents Hepatitis A Virus (HAV) strain characterization (period 2009-2020) from 18 states of India. For that, blood and stool samples (n ​= ​280) were screened for HAV RNA and sequences for 5'non-coding and VP3 regions were generated from positive samples (n ​= ​68).

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