A non-linear association of low-density lipoprotein cholesterol with all-cause and cardiovascular mortality among patients with hypertension.

Background: Although a few studies have examined the correlation between low-density lipoprotein cholesterol (LDL-C) and mortality, no study has explored these associations in hypertensive populations. This study aims to investigate the relationship between low-density lipoprotein cholesterol and cardiovascular and all-cause mortality in adults with hypertension.

Methods: Hypertensive participants aged ≥18 years from the National Health and Nutrition Examination Survey 1999-2018 with blood lipid testing data and complete follow-up data until 31 December 2019 were enrolled in the analysis.

Genome-wide identification and expression analysis of the WRKY gene family in during tissue development and salt stress.

is a traditional Chinese medicinal herb rich in various bioactive secondary metabolites, such as alkaloids and flavonoids, and exhibits remarkable resistance to abiotic stress. The WRKY transcription factor (TF) family is one of the largest plant-specific TF families and plays a crucial role in plant growth, development, and responses to abiotic stress. However, a comprehensive genome-wide analysis of the WRKY gene family in has not yet been conducted.

[Pediatric cardiac allograft transplantation: a clinicopathological study of twelve recipient hearts].

To analyze the morphologic changes and the extent of severity in end-stage heart disease; and to explore the correlation with their clinical features. Twelve cases of recipients who underwent pediatric cardiac allograft transplantation were collected from May 2022 to November 2023 at the Seventh Medical Center of People's Liberation Army of China General Hospital. Gross pathologic examinations were performed and morphological changes were observed under a light microscope after HE, Masson's trichrome, and reticulin staining.

HIV Pre-Exposure Prophylaxis Cascade Stages Among Men Who Have Sex With Men With Sexually Transmitted Infections in China: Multicenter Cross-Sectional Survey Study.

Background: There is limited literature available regarding the knowledge and use of HIV pre-exposure prophylaxis (PrEP) among men who have sex with men (MSM) with sexually transmitted infections (STIs).

Objective: This study's objective was to explore the HIV PrEP cascade stages (knowledge, willingness to use, and use) among MSM with STIs in China, in order to promote the implementation of PrEP in this population.

Methods: A cross-sectional study was conducted using a respondent-driven sampling method in 19 cities in China, from January to August 2022.