Microrheology of Ionic Liquid Doped Mucus for an Efficient Delivery of Protein-Based Oral Drugs.

Developing protein-based drugs for oral administration is one of the most challenging aspects of research due to their low stability and inability to permeate through intestinal mucus barrier. Recent studies suggest that the ionic liquids (ILs) can combine with protein-based drugs to improve stability and mucus-penetration capabilities. However, the interactions among protein-based drugs, ILs, and mucin are rather unknown, which can play a pivotal role in such drug delivery.

Dual-acting mechanism of microbial corrosion inhibition by ginger extract against nitrate-reducing bacteria in a nutrient-deficient environment.

This study investigates the efficacy of ginger extract (GE) as a green corrosion inhibitor in the petrochemical industry, specifically targeting microbial corrosion in carbon steel pipes utilized for river water coolant systems. The nutrient-deficient conditions coupled with the presence of nitrate-reducing bacteria (NRB) within these pipelines facilitate microbiologically influenced corrosion, wherein bacteria directly interact with the metal to harvest electrons for metabolic processes. Our findings indicate that GE inhibits microbial corrosion through dual mechanisms: significantly reducing biofilm formation and adsorbing onto the metal surface.

Attitude of Medical Students Toward Rising Violence Against Doctors.

Introduction: In the past three years, there has been an increase in incidents of violence against healthcare workers in Kerala. The aim of the study is to explore the attitude of medical students toward violence against doctors.

Methodology: This was a cross-sectional study undertaken at three of the four medical colleges in Ernakulam district in India as a part of our convenience sampling, which included around 1,500 students.