Publications by authors named "A Y Asahina"
Aberrant immune responses to viral pathogens contribute to pathogenesis, but our understanding of pathological immune responses caused by viruses within the human virome, especially at a population scale, remains limited. We analyzed whole-genome sequencing datasets of 6,321 Japanese individuals, including patients with autoimmune diseases (psoriasis vulgaris, rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), pulmonary alveolar proteinosis (PAP) or multiple sclerosis) and coronavirus disease 2019 (COVID-19), or healthy controls. We systematically quantified two constituents of the blood DNA virome, endogenous HHV-6 (eHHV-6) and anellovirus.
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- The study aims to analyze the characteristics and treatment of plexiform neurofibromas (PNs) in Japanese children with neurofibromatosis 1 (NF1), particularly with the introduction of the MEK inhibitor selumetinib.
- Primary and secondary surveys were conducted across numerous pediatric and dermatology departments in Japan, tracking 49 patients aged 3.3 to 18.8 years with PNs, commonly found on the face, neck, and head.
- The findings highlight early onset and significant morbidities like cosmetic disfigurement and pain, showing that selumetinib use is linked to these symptoms, stressing the importance of early diagnosis and the need for a multicenter registry to improve management strategies.
Introduction: is a member of the Gram-positive anaerobic cocci group and constitutes the flora of the skin and other parts of the body. It sometimes colonizes diabetic foot and rarely infects skin or soft tissue of non-immunocompromised patients.
Case Presentation: Here, we report the case of a severe subcutaneous abscess on the back caused by .