Publications by authors named "A Wronska"
Hemolymph enables communication between organs in insects and ensures necessary coordination and homeostasis. Its composition can provide important information about the physiological state of an insect and can have diagnostic significance, which might be particularly important in the case of harmful insects subjected to biological control. Linnaeus 1758 (Lepidoptera: Pyralidae) is a global pest to honey bee colonies.
View Article and Find Full Text PDFCytokines are highly conserved between mammals and insects. The present study examines the multiple effects of interferon-gamma (IFN-γ) application on the immunological defence mechanisms of Galleria mellonella larvae, invertebrates which are gaining popularity as a replacement for mammalian research models in immunological studies. G.
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- * This study examined how benzyl alcohol impacts the immune defense systems of wax moths, revealing significant changes in their cuticular lipid composition and immune responses.
- * Findings suggest that benzyl alcohol not only boosts certain protective proteins but also negatively affects insect cells, highlighting its potential as a non-toxic insecticide for vertebrates.
Heart failure, the leading cause of mortality and morbidity in the developed world, is characterized by cardiac ryanodine receptor 2 channels that are hyperphosphorylated, oxidized, and depleted of the stabilizing subunit calstabin-2. This results in a diastolic sarcoplasmic reticulum Ca leak that impairs cardiac contractility and triggers arrhythmias. Genetic mutations in ryanodine receptor 2 can also cause Ca leak, leading to arrhythmias and sudden cardiac death.
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- S100A1 is a small protein that helps control calcium levels in muscles, which is important for how they work.
- Researchers studied how S100A1 attaches to a big calcium channel in muscle cells called the ryanodine receptor (RyR).
- When calcium is present, S100A1 changes shape and sticks to RyR even more tightly, which could help scientists create new treatments for muscle diseases.