Publications by authors named "A Wirz"
Article Synopsis
- Laboratory Animal Allergy (LAA) affects a significant portion of laboratory animal workers, with 18% showing IgE positivity to mouse and/or rat allergens and 42% reporting allergic symptoms.
- The study evaluated 100 LAWs through questionnaires and IgE testing, revealing distinct categories: 17% were LAA positive, while 57% were LAA negative, with previous allergy symptoms influencing the results.
- The research introduces a standardized methodology for assessing IgE responses to animal allergens in the workplace, aiding in the understanding of LAA's immunological profile among workers.
Background & Aims: Central obesity promotes gastroesophageal reflux, which may be related to increased intra-abdominal pressure. We investigated the effect of increasing abdominal pressure by waist belt on reflux in patients with reflux disease.
Methods: We performed a prospective study of patients with esophagitis (n = 8) or Barrett's esophagus (n = 6); median age was 56 years and median body mass index was 26.
Objective: Gastric acid secretory capacity in different anatomical regions, including the postprandial acid pocket, was assessed in positive and negative volunteers in a Western population.
Design: We studied 31 positive and 28 negative volunteers, matched for age, gender and body mass index. Jumbo biopsies were taken at 11 predetermined locations from the gastro-oesophageal junction and stomach.
Background And Aims: Hiatus hernia (HH) is a key mediator of gastro-oesophageal reflux disease but little is known about its significance in the general population. We studied the structure and function of the gastro-oesophageal junction in healthy volunteers with and without HH.
Methods: We compared 15 volunteers with HH, detected by endoscopy or MRI scan, but without gastro-oesophageal reflux disease with 15 controls matched for age, gender and body weight.
Animal welfare depends on the possibility to express species-specific behaviours and can be strongly compromised in socially and environmentally deprived conditions. Nesting materials and refuges are very important resources to express these behaviours and should be considered as housing supplementation items. We evaluated the effects of one item of housing supplementation in standard settings in laboratory mice.
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