Publications by authors named "A Wirth"
Background: This study examined (1) associations between sociodemographic and clinical variables with low muscle mass and radiodensity and their loss relative to treatment commencement in patients with lung cancer; and (2) the magnitude of change in muscle mass and association with treatment outcomes and survival.
Methods: Prospective study in patients planned for curative (chemo)radiotherapy for lung cancer. Low skeletal muscle mass and radiodensity and muscle loss were determined from pre- and post-treatment computed tomography images.
The usage of high-quality learning applications (apps) at home may increase children's mathematical and literacy competencies. This approach was tested in a family intervention study. Intervention families (n = 302) in two German cohorts (N = 500; M (SD) = 61.
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- * Research in mice shows that the absence of certain TRPC channel proteins (specifically TRPC5) leads to a significant reduction in adrenaline release during insulin-induced hypoglycemia.
- * There is a newly identified signaling pathway where specific receptor activation leads to TRPC5 channel stimulation, impacting adrenaline secretion, with similar plasma metabolite changes noted in both TRPC5-deficient mice and HAAF patients.
Serotonin regulates multiple physiological and pathological processes in the brain, including mood and cognition. The serotonin receptors 5-HT1AR (also known as HTR1A) and 5-HT7R (also known as HTR7) have emerged as key players in stress-related disorders, particularly depression. These receptors can form heterodimers, which influence their functions.
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