Confirmation among college women: the eating disorders not otherwise specified diagnostic profile.

Unlabelled: Previously, the researchers proposed and tested a diagnostic framework for women with eating-related concerns who seek college health and mental health treatment. The framework emphasized moderate problems characterized by frequent binging, occasional purging, and frequent exercise; rumination; body image and self-esteem concerns; ambivalence about help seeking; and developmental themes. Several questions remained about the framework's generalizability beyond women in treatment.

Microbial Baeyer-Villiger oxidation: stereopreference and substrate acceptance of cyclohexanone monooxygenase mutants prepared by directed evolution.

[reaction: see text] An array of random mutants of cyclohexanone monooxygenase (CHMO) from Acinetobacter sp. NCIMB 9871 was screened against a library of structurally diverse ketones for modifications in the substrate acceptance profile and stereopreference of the enzymatic Baeyer-Villiger biooxidation. While the set of mutant biocatalysts was initially evolved for the enantiocomplementary oxidation of 4-hydroxycyclohexanone, improved and/or divergent stereoselectivities were observed for several substrates.