Publications by authors named "A Wiberg"
Micro-RNA Signature in CSF Before and After Autologous Hematopoietic Stem Cell Transplantation for Multiple Sclerosis.
Neurol Neuroimmunol Neuroinflamm
January 2025
Background And Objectives: MicroRNAs (miRNAs) are regulators of gene expression and have been reported to be dysregulated in people with multiple sclerosis (pwMS). Autologous hematopoietic stem cell transplantation (aHSCT) is an immune-ablative treatment intervention for pwMS. Currently, it is unknown if aHSCT affects expression levels of miRNAs in CSF.
View Article and Find Full Text PDFFocal nerve injuries are often associated with neuropathic pain. Preclinical research suggests altered neuroimmune signalling underlies such neuropathic pain; however, its cause remains poorly understood in humans. In this multicentre cohort study, we describe the local cellular and molecular signature of neuropathic pain at the lesion site, using Morton's neuroma as a human model system of neuropathic pain (n = 22; 18 women) compared with nerves from participants without nerve injury (n = 11; 4 women).
View Article and Find Full Text PDFArticle Synopsis
- Compulsive exercise is common in eating disorders, and the LEAP program is a cognitive behavioral therapy designed to address this issue over four weeks through group and individual sessions.* -
- Interviews with nine participants revealed that LEAP filled a treatment gap not addressed in their previous ED treatments, helping them develop awareness and change behaviors related to compulsive exercise.* -
- While LEAP was generally well-received, participants suggested the need for longer sessions and further exploration of the initial increase in physical activity experienced during the treatment.*
Identifying non-genetic factors associated with trigger finger.
J Plast Reconstr Aesthet Surg
July 2024
Article Synopsis
- A study was conducted using UK Biobank data to explore non-genetic factors associated with trigger finger (TF), focusing on a large population sample for more comprehensive insights.
- The analysis identified 2250 individuals with TF and revealed significant associations with factors such as age, female sex, body mass index, carpal tunnel syndrome, Dupuytren's disease, and diabetes, among others.
- The findings confirm known risk factors and introduce new associations, particularly emphasizing a strong link between TF and Dupuytren's disease, suggesting a shared underlying cause.
Introduction: Neuropathic pain is a highly prevalent condition associated with persistent disability. Some patients with neuropathic pain experience symptom spread outside neuroanatomical boundaries; these patients report more severe sensory symptoms and greater disability. However, the mechanisms behind such symptom spread are not fully understood.
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