Publications by authors named "A Welch"

Objective: To use egocentric network analysis (ENA) to identify how the role of social networks relates to e-cigarette use among college fraternity members.

Participants: 212 fraternity members participated in this study.

Methods: Hierarchical logistic regression analyses assessed the relationship between egocentric network variables and ever use and current use of e-cigarettes.

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Biomarkers of ageing serve as important outcome measures in longevity-promoting interventions. However, there is limited consensus on which specific biomarkers are most appropriate for human intervention studies. This work aimed to address this need by establishing an expert consensus on biomarkers of ageing for use in intervention studies via the Delphi method.

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Regional and global environmental challenges have become increasingly complex and require broader solutions than a single discipline can provide. Although there is a growing need for interdisciplinary research, many graduate education programs still train students within the confines of a particular discipline or specialty. The Ridge 2 Reef research traineeship program at the University of California, Irvine, aimed to provide transferable and interdisciplinary skill training to prepare graduate students from different disciplines to address current and future environmental challenges.

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Unlabelled: Recent studies report the genetic loss of the lariat debranching enzyme ( ) activity increases susceptibility to viral infection. Here, we show that more than 25% of human introns contain large hairpin structures created by the folding of two elements inserted in opposite orientation. In wildtype cells, this large reservoir of endogenous dsRNA is efficiently degraded.

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Article Synopsis
  • Spinal cord injury (SCI) below-level neuropathic pain is challenging to treat, but surgical lesions in the spinal cord’s dorsal root entry zone (DREZ) can target pain sources effectively.
  • A study with eight patients showed significant improvement in pain relief after neuroelectrically guided DREZ microcoagulation surgery, with some experiencing long-term relief for over a year.
  • Changes in brain connectivity were observed post-surgery, indicating that the procedure not only alleviated pain but also normalized brain function related to sensory and motor processing.
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