Effects of Tailored and ACT-Influenced Internet-Based CBT for Eating Disorders and the Relation Between Knowledge Acquisition and Outcome: A Randomized Controlled Trial.

This is the first trial to investigate the outcome of tailored and ACT-influenced, cognitive behavioral Internet treatment for eating disorder psychopathology, and the relation between knowledge acquisition and outcome. This study utilized a randomized controlled design, with computer-based allocation to treatment or waiting list control group. Participants were recruited via advertisements in social media and newspapers in Sweden.

Prevalence and risks factors of age-related macular degeneration in Oklahoma Indians: the Vision Keepers Study.

Objective: To determine the prevalence of age-related macular degeneration (AMD) and to identify its risk factors in an Oklahoma Indian population.

Design: Cross-sectional study design.

Participants: Included 1019 Oklahoma Indians who participated in baseline and second examinations of the Strong Heart Study.

Distinct functions of natural ADAM-15 cytoplasmic domain variants in human mammary carcinoma.

Adamalysins [a disintegrin and metalloproteinase (ADAM)] are a family of cell surface transmembrane proteins that have broad biological functions encompassing proteolysis, adhesion, and cell signal regulation. We previously showed that the cytoplasmic domain of ADAM-15 interacts with Src family protein tyrosine kinases and the adaptor protein growth factor receptor binding protein 2 (Grb2). In the present study, we have cloned and characterized four alternatively spliced forms of ADAM-15, which differ only in their cytoplasmic domains.

Visual impairment and eye abnormalities in Oklahoma Indians.

Objective: To determine the prevalence of visual impairment and eye abnormalities in Oklahoma Indians.

Methods: The cross-sectional study included 1019 Oklahoma Indians, aged 48 to 82 years; 60.2% were women.

Computer classification of nonproliferative diabetic retinopathy.

Objective: To propose methods for computer grading of the severity of 3 early lesions, namely, hemorrhages and microaneurysms, hard exudates, and cotton-wool spots, and classification of nonproliferative diabetic retinopathy (NPDR) based on these 3 types of lesions.

Methods: Using a computer diagnostic system developed earlier, the number of each of the 3 early lesions and the size of each lesion in the standard photographs were determined. Computer classification criteria were developed for the levels of individual lesions and for NPDR.