Increased urinary excretion of 1.4-methyl-imidazoleacetic acid in patients with atopic dermatitis.

To investigate whether the overall histamine turnover is increased in patients with atopic dermatitis, without respiratory disease, the urinary excretion of the main histamine metabolite 1.4-methyl-imidazoleacetic acid (MIAA) was examined in 23 patients and in 23 age- and sex-matched non-atopic controls. The patients excreted significantly more MIAA than the controls.

Pityrosporum orbiculare--a pathogenic factor in atopic dermatitis of the face, scalp and neck?

Pityrosporum orbiculare (pit.o.), the yeast form of Malassezia furfur, though usually considered to be a non-pathogenic saprophyte, in some individuals trigger various types of dermatitis.

Angioendotheliosarcoma of the nose--a case report.

Angioendotheliosarcoma of the face or scalp is regarded as a highly malignant tumor. We present a case with onset as a purple macule on the nose, suspected to be rosacea, and emphasize the use of early skin biopsy when a red or purple discoloration is seen in the face of elderly people.