Publications by authors named "A W van Eps"
Background: Traditional radiographic measurements of distal phalanx (Pd) displacement based on the outer hoof wall are not useful for diagnosis of acute laminitis.
Objectives: We hypothesised that the distance between the inner hoof wall and Pd ('lamellar lucent zone'; LLZ) measured on lateromedial digital radiographs would be increased in horses with acute and subacute laminitis compared with healthy horses.
Study Design: Retrospective cohort study and in vivo experimental study.
Article Synopsis
- The study evaluated a prototype dynamic laryngoplasty system (DLPS) on 7 healthy Standardbred horses to assess its feasibility for treating laryngeal issues.
- A standing surgical procedure induced complete laryngeal hemiplegia, and the DLPS showed effective delivery with no complications during the trial.
- Results indicated that while the DLPS could improve airway function 7 days post-surgery, long-term effects (1 month) were limited due to potential fibrosis around the implant.
Background: Horseshoes with modified contact surfaces combined with deformable ground substrates are used to change hoof orientation during mid-stance, for example, for therapeutic reasons.
Objectives: To measure the effect of horseshoes and ground substrates on sagittal and transverse plane hoof orientation at mid-stance using a dorsal hoof wall mounted triaxial accelerometer.
Study Design: In vivo experiment, randomised crossover design.
Background: A single dose of metformin administered 1 h prior to oral glucose challenge was previously shown to reduce insulinaemic responses in horses with experimentally-induced insulin dysregulation (ID). Targeted administration could be useful for controlling post-prandial hyperinsulinaemia in horses with naturally-occurring ID.
Objectives: The objective was to compare the insulinaemic and glycaemic responses to oral sugar testing (OST) performed at different intervals after a single dose of metformin in horses with naturally-occurring ID.
Background: Trazodone, a serotonin receptor antagonist and reuptake inhibitor, might be a useful adjunctive treatment in the initial management of horses with acute laminitis if it minimizes ambulation or encourages recumbency.
Objectives: (1) Evaluate the effects of PO trazodone on ambulatory activity and recumbency in healthy horses; and (2) assess the pharmacokinetics of multiple PO doses of trazodone.
Animals/methods: In a randomized cross-over design, 8 healthy horses received placebo or trazodone at 2 doses (2.