Publications by authors named "A W Thille"
Purpose: Predicting extubation failure remains a clinical challenge. This study aimed to determine diagnostic accuracy of models used at the bed side.
Methods: Post hoc analysis of 2341 patients at all risk included in five multicenter randomized trials.
Prophylactic Noninvasive Ventilation after Extubation of Obese Patients.
Am J Respir Crit Care Med
December 2024
A worldwide assessment of the mechanical ventilation in patients with acute exacerbations of chronic obstructive pulmonary disease. Analysis of the VENTILAGROUP over time. A retrospective, multicenter study.
Respir Res
December 2024
Background: The trend over time and across different geographical areas of outcomes and management with noninvasive ventilation or invasive mechanical ventilation in patients admitted for acute exacerbations of chronic obstructive pulmonary disease and treated with ventilatory support is unknown. The purpose of this study was to describe outcomes and identify variables associated with survival for patients admitted to an intensive care unit (ICU) with acute exacerbation of chronic obstructive pulmonary disease [aeCOPD] who received noninvasive or invasive mechanical ventilation worldwide.
Methods: Retrospective, multi-national, and multicenter studies, including four observational cohort studies, were carried out in 1998, 2004, 2010, and 2016 for the VENTILAGROUP following the same methodology.
Article Synopsis
- * In a case study, pneumonia caused by carbapenem-resistant Klebsiella pneumoniae showed cefiderocol resistance within just 32 days of treatment.
- * Genome sequencing revealed that the resistant bacteria carried mutations in siderophore receptor genes and were associated with the presence of certain β-lactamases, leading to increased resistance.