Publications by authors named "A W Macharia"
Introduction: We aimed to understand how the pandemic impacted work hours and employment status of female physicians. Methods: An anonymous survey of female physicians was distributed through social media and email lists from 12/2021 to 2/2022. Primary outcomes were changes in physicians' work schedules and employment status.
View Article and Find Full Text PDFBackground: The Dantu blood group variant protects against P. falciparum infections but its wider consequences have not been previously explored. Here, we investigate the impact of Dantu on susceptibility to bacteraemia.
View Article and Find Full Text PDFObjective: The primary objective was to determine if vaginal progesterone following cerclage for cervical length <10 mm or cervical dilation in patients without a history of spontaneous preterm birth (sPTB) decreased the risk of preterm birth at <34 weeks' gestation compared with cerclage alone. Secondary objectives were to determine if vaginal progesterone following cerclage (1) decreased the risk of preterm birth at <24, <28, and <37 weeks' gestation and (2) increased the latency period from cerclage placement to delivery compared with treatment with cerclage alone.
Study Design: Multicenter retrospective cohort study from 2015 to 2020 of singleton pregnancies, without prior sPTB, who had cerclage placement <24 weeks' gestation for cervical length <10 mm or cervical dilation.
Article Synopsis
- Kenya is struggling with health worker shortages and uneven distribution of healthcare resources, prompting the Ministry of Health to set standards for healthcare providers and infrastructure.
- A study was conducted to evaluate the effects of Universal Health Coverage (UHC) pilot programs on Human Resource for Health (HRH) using a mix of quantitative and qualitative methods across different counties.
- Data collection involved a detailed assessment of available healthcare resources and staff at health facilities using specific tools, with findings analyzed statistically to compare UHC pilot counties with non-UHC ones.
Article Synopsis
- Blood group O provides protection against severe malaria, while non-O blood groups (such as AA, AB, BB, and AO) are associated with increased risk and larger P. falciparum-host red blood cell rosettes.
- The study tested whether double dose non-O genotypes (AA, BB, AB) have a higher risk of severe malaria compared to single dose heterozygotes (AO, BO) among Kenyan children.
- Results indicated that double dose genotypes had significantly higher odds ratios for severe malaria and formed larger rosettes in vitro, supporting the idea that these genotypes increase susceptibility to malaria pathology.