Factors influencing scrotal temperature in the bull during simulated heat treatments and thermoneutral conditions as determined by multimodel inferencing.

The creation of any model is complex requiring vast amounts of data, typically gathered over a series of experiments. Specifically the temperature humidity index (THI) and heat load index (HLI) are used as management tools to implement mitigation strategies during hot climatic conditions. Exposure of the testes to hot climatic conditions has a negative impact on spermatogenesis in the bull, and other species.

The α-synuclein seed amplification assay: Interpreting a test of Parkinson's pathology.

The α-synuclein seed amplification assay (αSyn-SAA) sensitively detects Lewy pathology, the amyloid state of α-synuclein, in the cerebrospinal fluid (CSF) of patients with Parkinson's disease (PD). The αSyn-SAA harnesses the physics of seeding, whereby a superconcentrated solution of recombinant α-synuclein lowers the thermodynamic threshold (nucleation barrier) for aggregated α-synuclein to act as a nucleation catalyst ("seed") to trigger the precipitation (nucleation) of monomeric α-synuclein into pathology. This laboratory setup increases the signal for identifying a catalyst if one is present in the tissue examined.

Testing the Taguchi method to design and analyze integrated disease management strategies, for the control of late blight (Phytophthora infestans) on potato.

Background: Identifying robust integrated pest management (IPM) strategies requires the testing of multiple factors at the same time and assessing their combined effects e.g., on disease control.

An Investigation into Anion Sensing of the Molecular Aggregate of 4-(Pyrrol-1-yl)pyridine and Its Derivatives.

Recently, 4-(pyrrol-1-yl)pyridine has been found to act as a supramolecular chemodosimeter, sensing nitrite ions in an aqueous solution with naked eye detection and a low limit of detection of 0.330 ppm. This work explores the anion-sensing properties of related derivatives, 4-(2,5-dimethyl-pyrrol-1-yl)pyridine and 4-(2,4-dimethyl-pyrrol-1-yl)pyridine, and provides a comparison with the parent compound.