Publications by authors named "A W Kimball"
Background: Hidradenitis suppurativa (HS) affects different patient populations that require unique considerations in their management. However, no HS guidelines for these populations exist.
Objective: To provide evidence-based consensus recommendations for patients with HS in seven special patient populations: i) pregnancy, ii) breastfeeding, iii) pediatrics, iv) malignancy, v) tuberculosis infection, vi) hepatitis B or C infection, and vii) HIV disease.
Background: SUNSHINE and SUNRISE demonstrated sustained clinical efficacy of secukinumab in patients with moderate-to-severe hidradenitis suppurativa (HS) through 52 weeks. Patients completing the core trials could enter a 4-year extension trial.
Objectives: To evaluate the long-term efficacy, safety/tolerability, and maintenance of clinical response of secukinumab through Week 104 in the extension trial.
Article Synopsis
- Menstrually related mood disorder (MRMD) is characterized by severe emotional symptoms occurring in the late luteal phase of the menstrual cycle, which may be linked to low levels of the neuroactive steroid allopregnanolone due to lesser conversion from progesterone.
- In a study with nine women with MRMD and fourteen healthy controls, MRMD was diagnosed using the DSM-5 criteria, and symptoms of depression and anxiety, as well as plasma neuroactive steroid levels, were assessed at different phases of the menstrual cycle.
- Results showed that while women with MRMD had higher allopregnanolone levels in the mid-follicular phase, they experienced greater depression severity only in the late luteal phase, suggesting a
Introduction Hidradenitis suppurativa (HS) is a debilitating, inflammatory skin disorder. Treatment strategies in patients with HS are challenging; real-world evidence in a HS population is warranted for greater disease understanding. The objective of this analysis was to describe real-world treatment patterns and treatment satisfaction in patients with HS.
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