Plasma levels of glial fibrillary acidic protein and neurofilament light chain in patients with chronic migraine: a multicenter case-control study.

Objective: Plasma glial fibrillary acidic protein (pGFAP) and plasma neurofilament light chain (pNfL) levels reflect astrocyte activation and neuronal damage, respectively. Whether these phenomena play a role in migraine is unknown. This study aimed to compare pGFAP and pNfL levels in patients with chronic migraine (CM) and age-matched controls and to analyze their relation with clinical features.

Pest categorisation of .

Following the commodity risk assessment of plants grafted on from China, in which (Hemiptera: Diaspididae) was identified as a pest of possible concern, the European Commission requested the EFSA Panel on Plant Health to conduct a pest categorisation of for the territory of the European Union (EU). The origin of the scale insect is uncertain, with either South America or eastern Asia suggested as the native range. The geographic distribution of the species includes many countries of the continents of Africa, North and South America, Asia and Oceania.

Pest categorisation of .

Following the commodity risk assessment of and plants for planting from Türkiye, in which (Hemiptera: Diaspididae), the pistachio oyster scale or yellow pistachio scale, was identified as a pest of possible concern, the EFSA Panel on Plant Health performed a pest categorisation for the territory of the European Union (EU). is reported as a polyphagous pest which, however, mainly affects plants of the genus Originating from Asia, it is widely distributed in pistachio producing countries of Central, South and West Asia. Within the EU, the pest has been reported from Cyprus and Greece.

Oscillometry reference values for children and adolescents.

Background: Oscillometry devices allow quantification of respiratory function at tidal breathing but device-specific reference equations are scarce: the present study aims to create sex-specific oscillometric reference values for children and adolescents using the Resmon PRO FULL device.

Methods: Healthy participants (n=981) aged 6 to 17 years of the Austrian LEAD general population cohort were included. Subjects had normal weight (body mass index ≤99th percentile) and normal lung volumes (total lung capacity (TLC) ≥ lower limit of normal).

Circulating tumor DNA dynamics and clinical outcome in metastatic colorectal cancer patients undergoing front-line chemotherapy.

Purpose: we tested whether ctDNA changes may be used to assess early response and clinical outcome in metastatic colorectal cancer (mCRC) patients undergoing front-line systemic anti-cancer therapy (SACT).

Experimental Design: 862 plasma samples were collected 4-weekly from baseline (BL) until disease progression in mCRC patients receiving front line SACT. ctDNA normalization was defined as ≥99% clearance after 1 month of therapy (Mo1) in the 3 variants with the highest allele frequency in BL ctDNA.